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In a clinical study, a group of patients where treated for 12 months with 20mg of rimonabant (Acomplia or Zimulti). And lost an average 20lbs verses the placebo group that lost 5 lbs. About 75% lost over 5% of their body weight and about 44% lost more than 10% of their body weight. The study also took into consideration some cardiovascular risks and found significant benefits including a 23% increase in "Good Cholesterol" levels (HDL-cholesterol - a high level seems to protect against heart attack.) There was an average reduction of 15% in triglycerides (the chemical form in which most fat exists in the body and are associated with cholesterol)
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